Obesity Alert – Is Obesity Ageing Your Brain?

According to a study by Cambridge and Yale University, obesity makes you age ten times faster than your lean counterparts. Further, scientists found that the shrinkage of brain is much more prevalent in overweight people from middle-age onward and not so much in the 20s and 30s. Dr. Ramen Goel, Founder, Centre for Metabolic Surgery, says, “We already know that obesity is very damaging to the heart, joints, knees, hips, livers and a risk factor of many diseases. It was a matter of time before we learnt its impact on the brain. We are only starting to learn how the pounds on your waist shrink the matter in your brain, ageing could just be the tip of the iceberg.”

Are you the type of person who’d rather eat a cupcake than a carrot?

Bad news alert.

A credible, new study by the Cambridge and the Yale University has validated ‘you are what you eat.’ Obesity makes you age ten times faster than your lean counterparts.

The effects of fat on the heart, liver, kidneys and other organs were known but the fact that it can impair cognition, memory and white matter is startling.

Is That Burger Shrinking Your Brain?

The fact that your brain shrinks with age is well known but does it cause any other characteristic changes? To find out, researchers looked into the head of 473 people of all shapes and sizes between the ages of 20 and 87 years. And they were shocked to see that the white matter density of overweight/obese individuals had aged 10 years more than their slimmer mates.

For all those who don’t remember school biology, white matter is that tissue which determines how well you function and learn, it also passes information between various areas of the brain.

Scientists found that the shrinkage of brain is much more prevalent in overweight people from middle-age onward and not so much in the 20s and 30s.

The overall message is that the brain ages 10 years faster if you are obese. It is not clear why such damages occur or if obesity affects the brain or it’s vice versa.

Lisa Ronan, Author, University of Cambridge

The big question then, can obesity trigger dementia? At the moment, researchers don’t know that yet and more follow up is needed to study that.

Meanwhile, noted metabolic and obesity specialist in Mumbai, Dr Ramen Goel is not at all surprised to learn these findings.

We already know that obesity is very damaging to the heart, joints, knees, hips, livers and a risk factor of many diseases. It was a matter of time before we learnt its impact on the brain. We are only starting to learn how the pounds on your waist shrink the matter in your brain, ageing could just be the tip of the iceberg.

Dr Ramen Goel, Director Bariatric and Metabolic Surgeon, Wockhardt Hospitals

And that’s unsettling.

A study published in the American Geriatric Societylooked at the memory scores of 65 to 79 year olds and found that for every 1-point increase in the individual’s body mass index, there was a 1-point decrease on a memory test.

Clearly, packing on the pounds can not just alter your waistline, it can alter your brain, memory, learning and cognitive functions too.

Plan to put down that burger soon?

‘Obesity Is Far More Complex Than We Know’

Till now, scientists haven’t been able to understand how the excess fat affects the brain and why this impacts mostly those past their prime. But another study published in The Journal of Neuroscience attempts to explain how obesity has such a detrimental impact on the brain.

Now fat cells release chemicals into the bloodstream that flow to all the organs and muscles and this leads to inflammation which cause diseases like fatty liver, heart problems among others.

In a nut shell, scientists injected fat pads into lean lab rats and they immediately became dimmer, duller, performed poorly on previously done cognitive tests. Further scans revealed that chemicals in the fat cells rendered the blood-barrier leaky, permeable and vulnerable to attacks on the brain.

Of course both the obesity-brain studies have their shortcomings:

1) The first does not necessarily conclude if obesity causes brain ageing or brain changes cause obesity.

2) The latter is done on mice, and mice humans are no lab rats.

However, what’s not contested is that India is the third most obese country in the world, a-third of our people are at a risk of dying prematurely from weight related complications. There is no reason why you shouldn’t make weight loss your mission for the year.

Article Source: www.thequint.com